Clinical trials in Brest – page 21

584 clinical trials in Brest, France across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

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584

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584 trials in Brest

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PIK3CA related overgrowth spectrum

Recruiting

Study on the Effects and Safety of Alpelisib for Children and Adults with Megalencephaly-Capillary Malformation Polymicrogyria Syndrome

Registered drug

Study on the Effects and Safety of Alpelisib for Children and Adults with Megalencephaly-Capillary Malformation Polymicrogyria Syndrome

Registered drug

France

Participants:0–17 years · 18–64 years
Substances:Alpelisib
Sponsor:Centre Hospitalier Universitaire De Dijon

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Adrenocortical carcinoma

Recruiting

Study on Mitotane Alone or with Cisplatin and Etoposide for Patients with High-Risk Adrenocortical Carcinoma After Surgery

Registered drugNo placebo

Study on Mitotane Alone or with Cisplatin and Etoposide for Patients with High-Risk Adrenocortical Carcinoma After Surgery

Registered drugNo placebo

France

Participants:18–64 years · 65+ years
Substances:Cisplatin
Sponsor:Amsterdam UMC Stichting

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Chronic kidney disease+1

Recruiting

Study on Blood Pressure Management with Amiloride Hydrochloride, Indapamide, and Furosemide for Patients with Uncontrolled Hypertension and Chronic Kidney Disease

Registered drugNo placebo

Study on Blood Pressure Management with Amiloride Hydrochloride, Indapamide, and Furosemide for Patients with Uncontrolled Hypertension and Chronic Kidney Disease

Registered drugNo placebo

France

Participants:18–64 years · 65+ years
Substances:Furosemide
Sponsor:Centre Hospitalier Regional Universitaire De Tours

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Anaplastic large cell lymphoma T- and null-cell types

Recruiting

Study on Vinblastine for Children and Adolescents with Standard Risk ALK-Positive Anaplastic Large Cell Lymphoma

Registered drugNo placebo

Study on Vinblastine for Children and Adolescents with Standard Risk ALK-Positive Anaplastic Large Cell Lymphoma

Registered drugNo placebo

France

Participants:0–17 years
Substances:Vinblastine Sulfate
Sponsor:GPOH gGmbH

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Eastern Cooperative Oncology Group performance status

Recruiting

Study on Tocilizumab and Prednisolone for Arthritis Caused by Cancer Immunotherapy in Cancer Patients

Registered drugNo placebo

Study on Tocilizumab and Prednisolone for Arthritis Caused by Cancer Immunotherapy in Cancer Patients

Registered drugNo placebo

France

Participants:18–64 years · 65+ years
Substances:Prednisolone
Sponsor:Karolinska University Hospital

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Pulmonary embolism+3

Recruiting

Study on the Best Antithrombotic Therapy for Patients with Acute Venous Thromboembolism Using Tinzaparin Sodium and Drug Combination

Registered drugNo placebo

Study on the Best Antithrombotic Therapy for Patients with Acute Venous Thromboembolism Using Tinzaparin Sodium and Drug Combination

Registered drugNo placebo

France

Participants:18–64 years · 65+ years
Substances:Acenocoumarol
Sponsor:Centre Hospitalier Universitaire De Saint Etienne

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Glioma

Recruiting

Study on Fluorodopa (18F) for Diagnosing Low-Grade Glioma in Patients Without MRI Contrast Enhancement

Registered drugNo placebo

Study on Fluorodopa (18F) for Diagnosing Low-Grade Glioma in Patients Without MRI Contrast Enhancement

Registered drugNo placebo

France

Participants:18–64 years · 65+ years
Substances:Fluorodopa (18F)
Sponsor:CHRU De Nancy

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Anti-neutrophil cytoplasmic antibody positive vasculitis

Recruiting

Study on Pioglitazone for Improving Kidney Health in Patients with ANCA-Associated Vasculitis

Registered drug

Study on Pioglitazone for Improving Kidney Health in Patients with ANCA-Associated Vasculitis

Registered drug

France

Participants:18–64 years · 65+ years
Substances:Dexchlorpheniramine
Sponsor:Assistance Publique Hopitaux De Paris

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Testicular germ cell tumour

Recruiting

Study on Preventing Blood Clots in Patients with Advanced Germ Cell Tumors Using Cisplatin and a Drug Combination

Registered drugNo placebo

Study on Preventing Blood Clots in Patients with Advanced Germ Cell Tumors Using Cisplatin and a Drug Combination

Registered drugNo placebo

France

Participants:18–64 years
Substances:Cisplatin
Sponsor:Institut Gustave Roussy

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Acute myeloid leukaemia (in remission)

Recruiting

Study Comparing Clofarabine/Busulfan and Fludarabine/Busulfan for Adults with Acute Myeloid Leukemia Eligible for Stem Cell Transplantation

Registered drugNo placebo

Study Comparing Clofarabine/Busulfan and Fludarabine/Busulfan for Adults with Acute Myeloid Leukemia Eligible for Stem Cell Transplantation

Registered drugNo placebo

France

Participants:18–64 years · 65+ years
Substances:Busulfan
Sponsor:Centre Hospitalier Universitaire De Nantes

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Prostate cancer metastatic

Recruiting

Study on the Effectiveness of ADT with or without Darolutamide in Men with Newly Diagnosed Metastatic Prostate Cancer and Limited Functional Ability

InvestigationalNo placebo

Study on the Effectiveness of ADT with or without Darolutamide in Men with Newly Diagnosed Metastatic Prostate Cancer and Limited Functional Ability

InvestigationalNo placebo

France

Participants:18–64 years · 65+ years
Substances:Darolutamide
Sponsor:Unicancer

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Congenital cystic kidney disease

Recruiting

Study on Hydrochlorothiazide and Tolvaptan for Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Registered drug

Study on Hydrochlorothiazide and Tolvaptan for Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Registered drug

France

Participants:18–64 years · 65+ years
Substances:Hydrochlorothiazide
Sponsor:Universitair Medisch Centrum Groningen

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Clinical research in Brest

What the registry says about research in the country

01 Oncology Research

Groundbreaking trials focusing on head and neck squamous cell carcinoma, exploring innovative treatments combining radiotherapy with targeted therapies. Studies also examine new approaches for esophageal cancer and pancreatic adenocarcinoma.

Advanced Cancer Therapies
Combination Treatments
Targeted Therapeutics

Multiple trials are investigating novel drug combinations and immunotherapy approaches for various cancer types.

02 Autoimmune Conditions

Comprehensive research into Sjögren's syndrome treatment options, including innovative biological therapies and histopathological studies. Additional focus on rheumatoid arthritis and novel therapeutic approaches.

Biological Treatments
Disease Mechanisms
Treatment Response

Studies aim to understand disease mechanisms and evaluate new therapeutic options for autoimmune disorders.

03 Cardiovascular and Respiratory Studies

Investigation of treatments for pulmonary arterial hypertension and heart failure prevention. Research includes innovative drug combinations and preventive approaches for cardiovascular conditions.

Heart Failure Prevention
Hypertension Management
Asthma Control

Focus on developing effective treatments for chronic cardiovascular and respiratory conditions.

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