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Clinical trials in Sofia – page 25

763 clinical trials in Sofia, Bulgaria across 17 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

Sofia at a glance
763
clinical trials
  • Research sites17
Type of trial
Recruitment status
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763 trials in Sofia

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Asthma

Not yet recruiting

Study of Three Doses of Frevecitinib (KN-002) in Adults with Severe Asthma Not Controlled by Medium‑to‑High Dose Inhaled Steroid/LABA Therapy

Registered drug
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Salbutamol Sulfate

Adrenogenital syndrome

Not yet recruiting

Study of Crinecerfont in Adults with Classic Congenital Adrenal Hyperplasia to Reduce Androgen Levels

InvestigationalNo placebo
Countries:BulgariaBulgaria
  • Participants:18–64 years
  • Substances:Crinecerfont
  • Sponsor:Neurocrine Biosciences Inc.

Rheumatoid arthritis

Not yet recruiting

ELV001 for Active Rheumatoid Arthritis in Patients with Inadequate Response to Methotrexate and Tumor Necrosis Factor Inhibition

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years

Bipolar I disorder

Not yet recruiting

A study to evaluate the safety and effectiveness of azetukalner in patients with bipolar depression

InvestigationalNo placebo
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Azetukalner
  • Sponsor:Xenon Pharmaceuticals Inc.

Idiopathic pulmonary fibrosis

Not yet recruiting

A study to evaluate the safety and effectiveness of zampilimab in people with idiopathic pulmonary fibrosis

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:ZAMPILIMAB
  • Sponsor:Chiesi Farmaceutici S.p.A.

Dermatitis atopic

Not yet recruiting

Phase 2b Randomized Double‑Blind Study of Oral PF‑08049820 in Adults with Moderate to Severe Atopic Dermatitis

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years
  • Sponsor:Pfizer Inc.

Axial spondyloarthritis+1

Not yet recruiting

Study to evaluate the effect of upadacitinib on the frequency of eye inflammation in patients with axial spondyloarthritis.

Registered drugNo placebo
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Upadacitinib
  • Sponsor:Care Arthritis Ltd.

Bipolar I disorder

Not yet recruiting

A study to evaluate the effectiveness and safety of azetukalner in patients experiencing depressive episodes associated with bipolar disorder.

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Azetukalner
  • Sponsor:Xenon Pharmaceuticals Inc.

Pancreatic carcinoma metastatic+1

Not yet recruiting

A Study of Ponsegromab Combined with Chemotherapy for Adults with Pancreatic Cancer that has Spread and Caused Weight Loss

Registered drug
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Ponsegromab
  • Sponsor:Pfizer Inc.

Conjunctivitis allergic+1

Not yet recruiting

A Study Comparing Tacrolimus and Ciclosporin Eye Drops for Children and Adults with Moderate to Severe Vernal Keratoconjunctivitis

Registered drugNo placebo
Countries:BulgariaBulgaria
  • Participants:0–17 years
  • Substances:Ciclosporin
  • Sponsor:Laboratoires Thea

Immune thrombocytopenia

Not yet recruiting

Study on the Safety and Effectiveness of Budoprutug in Patients with Immune Thrombocytopenia

InvestigationalNo placebo
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:BUDOPRUTUG
  • Sponsor:Climb Bio Inc.

Abdominal infection+5

Not yet recruiting

Study on Aztreonam, Avibactam, and Metronidazole for Treating Infections in Neonates and Infants Under 9 Months with Gram-Negative Bacterial Infections

Registered drugNo placebo
Countries:BulgariaBulgaria
  • Participants:0–17 years
  • Substances:Avibactam Sodium
  • Sponsor:Pfizer Inc.

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Clinical research in Sofia

What the registry says about research in the country

01 Respiratory Research

Clinical studies focusing on respiratory infections and conditions, including trials for RSV, human metapneumovirus, and influenza vaccines in older adults. Research also includes investigations into asthma treatments and chronic rhinosinusitis management.

  • Respiratory Syncytial Virus (RSV)
  • Influenza Prevention
  • Chronic Rhinosinusitis
  • Asthma Management
02 Dermatological Studies

Comprehensive research into various skin conditions, evaluating new treatments for chronic urticaria, hidradenitis suppurativa, and different forms of psoriasis. These trials aim to improve patient outcomes through innovative therapeutic approaches.

  • Chronic Spontaneous Urticaria
  • Hidradenitis Suppurativa
  • Genital Psoriasis
  • Plaque Psoriasis
03 Autoimmune Disorders

Groundbreaking studies examining treatments for various autoimmune conditions, including multiple sclerosis, Sjögren's disease, and systemic sclerosis. Research focuses on developing targeted therapies to manage these chronic conditions.

  • Multiple Sclerosis
  • Sjögren's Disease
  • Systemic Sclerosis
  • Psoriatic Arthritis
04 Metabolic and Cardiovascular Research

Studies investigating treatments for metabolic disorders and heart conditions, including research on hypertriglyceridemia, obesity management, and heart failure prevention. Focus on both therapeutic interventions and preventive measures.

  • Hypertriglyceridemia
  • Obesity Management
  • Heart Failure Prevention
  • Cardiovascular Health
05 Oncology Research

Advanced clinical trials focusing on breast cancer treatments and blood disorders, particularly investigating new therapeutic approaches for advanced/metastatic breast cancer and myelodysplastic syndrome.

  • Advanced Breast Cancer
  • Myelodysplastic Syndrome
  • Targeted Therapies
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