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Cardiac disorders – page 5

  • 481 clinical trials
  • 225 recruiting
  • 172 conditions
  • 28 countries

Conditions in this area

172 conditions with trials, the busiest first

Atrial fibrillation55Cardiac failure42Coronary artery disease37Acute myocardial infarction30Cardiac amyloidosis29Acute coronary syndrome21Cardiac arrest19Cardiac failure chronic17Cardiovascular disorder16Heart failure with reduced ejection fraction16Hypertrophic cardiomyopathy16Cardiac failure acute14Glycogen storage disease type II14Heart failure with preserved ejection fraction13Myocardial infarction13Cardiomyopathy11Myocardial ischaemia11Cardiogenic shock10Chronic coronary syndrome10Dilated cardiomyopathy9Myocarditis9Aortic valve stenosis7Chronic kidney disease6Trisomy 216+148

Clinical trials in Cardiac disorders

481 trials across Europe, recruiting first

Type of trial
Recruitment status
Quick filters

481 clinical trials

Trisomy 21

Recruiting

Study of AEF0217 compared to placebo for improving behavior and thinking skills in adults and older adolescents with Down syndrome

Investigational
Countries:FranceFrance
  • Participants:0–17 years · 18–64 years
  • Substances:1-((3S,8S,9S,10R,13S,14S,17S)3-BENZYLOXY-10,13,17-TRIMETHYL-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1HCYCLOPENTA[A]PHENANTHRENE-17-YL)ETHAN-1-ONE
  • Sponsor:Aelis Farma

Cardiac failure

Recruiting

A Study Testing Drug Combination for Heart Failure in Women Comparing Increased Doses to Standard Care

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Bisoprolol
  • Sponsor:Policlinico San Donato S.p.A.

Atrial fibrillation

Recruiting

A Study to Test How Well PKN605 Works and How Safe It Is in Patients with Atrial Fibrillation

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Sponsor:Novartis Pharma AG

Hypertrophic cardiomyopathy+1

Recruiting

A study testing ninerafaxstat compared to placebo in patients with symptomatic non-obstructive hypertrophic cardiomyopathy

Investigational
Countries:AustriaAustria
  • Participants:18–64 years · 65+ years
  • Sponsor:Imbria Pharmaceuticals Inc.

Cardiac failure

Recruiting

A study testing the reduction of heart failure drug combination in patients with heart failure in remission

Registered drugNo placebo
Countries:BelgiumBelgium
  • Participants:18–64 years · 65+ years
  • Substances:Bisoprolol Fumarate
  • Sponsor:Ziekenhuis Oost Limburg

Cardiomyopathy

Recruiting

Study of stopping heart failure medications in patients with non-ischemic cardiomyopathy who responded very well to cardiac resynchronization therapy

Registered drugNo placebo
Countries:SpainSpain
  • Participants:18–64 years · 65+ years
  • Substances:Altizide
  • Sponsor:Andrea Di Marco

Ventricular tachycardia

Recruiting

Study of AGP100 Safety and Effectiveness in Patients with Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

InvestigationalNo placebo
Countries:NorwayNorway
  • Participants:18–64 years · 65+ years
  • Sponsor:Agiana Pharmaceuticals AS

Familial dilated cardiomyopathy

Recruiting

Study of ALXN2350 gene therapy in adults with BAG3 mutation-associated dilated cardiomyopathy: A safety and efficacy trial

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:AAV9-CTNT-COBAG3
  • Sponsor:Alexion Pharmaceuticals Inc.

Coronary artery disease+1

Recruiting

Study comparing high-dose and low-dose aspirin with prasugrel and aspirin combination in patients after coronary artery bypass grafting surgery

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Acetylsalicylic Acid
  • Sponsor:Agencja Badań Medycznych

Study of glucagon effects on physical capacity in patients with heart failure with preserved ejection fraction (HFpEF) with or without liver steatosis

Recruiting
Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Glucagon
  • Sponsor:Katholisches Klinikum Bochum gGmbH

Acute myocardial infarction

Recruiting

Study of ziltivekimab compared to placebo in patients with acute heart attack to evaluate its effects on coronary artery plaque reduction

Investigational
Countries:AustriaAustria
  • Participants:18–64 years · 65+ years
  • Substances:Ziltivekimab
  • Sponsor:ECRI-trials B.V.

Cardiomyopathy

Recruiting

Study of Nucresiran in Adults with Transthyretin Amyloidosis with Cardiomyopathy to Evaluate its Effects on Survival and Heart Problems

Investigational
Countries:AustriaAustria
  • Participants:18–64 years · 65+ years
  • Sponsor:Alnylam Pharmaceuticals Inc.

Substances studied in this area

The therapies tested most often in Cardiac disorders trials.

Acetylsalicylic Acid44 clinical trialsClopidogrel30 clinical trialsTicagrelor27 clinical trialsSodium Chloride25 clinical trialsDapagliflozin22 clinical trialsApixaban21 clinical trialsEmpagliflozin20 clinical trialsRivaroxaban19 clinical trialsPrasugrel18 clinical trials
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