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Respiratory, thoracic and mediastinal disorders – page 58

  • 1 276 clinical trials
  • 446 recruiting
  • 379 conditions
  • 28 countries

Conditions in this area

379 conditions with trials, the busiest first

Non-small cell lung cancer327Asthma88Non-small cell lung cancer metastatic82Chronic obstructive pulmonary disease60Non-small cell lung cancer stage IV57COVID-1939Pulmonary arterial hypertension38Non-small cell lung cancer stage III37Idiopathic pulmonary fibrosis34Pneumonia32Small cell lung cancer32Non-small cell lung cancer stage IIIB31Small cell lung cancer extensive stage31Influenza28Interstitial lung disease28Lung neoplasm malignant28Cystic fibrosis24Conjunctivitis allergic23Pulmonary hypertension23Chronic rhinosinusitis with nasal polyps21Respiratory syncytial virus infection20Rhinitis allergic20Post-acute COVID-19 syndrome19Ovarian cancer18+355

Clinical trials in Respiratory, thoracic and mediastinal disorders

1 276 trials across Europe, recruiting first

Type of trial
Recruitment status
Quick filters

1 276 clinical trials

Seasonal allergy

Not recruiting

Effect of a single oral dose of acalabrutinib on skin prick test wheal size in adults with grass pollen allergy using histamine dihydrochloride and phleum pratense

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Acalabrutinib
  • Sponsor:Alk-Abello A/S

Non-small cell lung cancer metastatic

Not recruiting

Phase 3 Study of Subcutaneous Pembrolizumab with Hyaluronidase vs. Intravenous Pembrolizumab in Metastatic NSCLC with PD-L1 TPS ≥50%

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Pembrolizumab
  • Sponsor:Merck Sharp & Dohme LLC

Respiratory syncytial virus infection

Not recruiting

Relative Bioavailability of Sisunatovir Capsules vs Tablets in Fasted and Fed Conditions in Healthy Adults with Respiratory Syncytial Virus

InvestigationalNo placebo
Countries:BelgiumBelgium
  • Participants:18–64 years · 65+ years · Healthy volunteers
  • Substances:Sisunatovir
  • Sponsor:Pfizer Inc.

Asthma

Not recruiting

Evaluation of lung delivery and systemic exposure of inhaled beclometasone dipropionate and beclometasone dipropionate anhydrous for asthma in healthy adult volunteers

Registered drugNo placebo
Countries:BelgiumBelgium
  • Participants:18–64 years · Healthy volunteers
  • Substances:Beclometasone Dipropionate
  • Sponsor:Chiesi Farmaceutici S.p.A.

Respiratory syncytial virus infection

Not recruiting

Safety, Tolerability, and Pharmacokinetics of MK-3508 in Healthy Adults for Treatment of Respiratory Syncytial Virus Infection

Investigational
Countries:BelgiumBelgium
  • Participants:18–64 years · Healthy volunteers
  • Sponsor:Merck Sharp & Dohme LLC

Chronic obstructive pulmonary disease

Not recruiting

EP395 and drug combination (verapamil, midazolam, digoxin) pharmacokinetic study in healthy volunteers with COPD

Registered drugNo placebo
Countries:SwedenSweden
  • Participants:18–64 years · Healthy volunteers
  • Substances:Digoxin
  • Sponsor:Epiendo Pharmaceuticals ehf.

Respiratory syncytial virus infection

Not recruiting

A study to evaluate the taste of sisunatovir and denatonium benzoate in healthy adults for the treatment of respiratory syncytial virus (RSV)

InvestigationalNo placebo
Countries:BelgiumBelgium
  • Participants:18–64 years · 65+ years · Healthy volunteers
  • Substances:Sisunatovir
  • Sponsor:Pfizer Inc.

Cystic fibrosis

Not recruiting

Bioequivalence Study of Ivacaftor 150 mg Film‑Coated Tablets in Healthy Adults for Cystic Fibrosis

Registered drugNo placebo
Countries:RomaniaRomania
  • Participants:18–64 years · Healthy volunteers
  • Substances:Ivacaftor
  • Sponsor:Sun Pharmaceutical Industries Limited

Non-small cell lung cancer

Not recruiting

A study to evaluate how lazertinib is absorbed in healthy adults to support future treatment for non-small cell lung cancer.

InvestigationalNo placebo
Countries:BelgiumBelgium
  • Participants:18–64 years · Healthy volunteers
  • Substances:Lazertinib
  • Sponsor:Janssen Cilag International

Pneumonia

Not recruiting

Bioequivalence Study of Amoxicillin/Clavulanic Acid Oral Suspension Compared with Reference Product in Healthy Adult Volunteers under Fed Conditions

Registered drugNo placebo
Countries:CzechiaCzechia
  • Participants:18–64 years · Healthy volunteers
  • Substances:Amoxicillin
  • Sponsor:Tarchominskie Zaklady Farmaceutyczne Polfa S.A.

COVID-19

Not recruiting

PF-07817883 Oral Tablet Bioavailability Study in Healthy Adults to Support Treatment of COVID‑19

InvestigationalNo placebo
Countries:BelgiumBelgium
  • Participants:18–64 years · 65+ years · Healthy volunteers
  • Substances:IBUZATRELVIR
  • Sponsor:Pfizer Inc.

Gastric cancer+6

Not recruiting

A Study of CLDN6 CAR-T Cell Therapy With or Without CLDN6 RNA-LPX Vaccine in Patients With CLDN6-Positive Advanced Solid Tumors That Returned or Did Not Respond to Treatment

InvestigationalNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Cldn6 Car-T
  • Sponsor:BioNTech Cell & Gene Therapies GmbH

Substances studied in this area

The therapies tested most often in Respiratory, thoracic and mediastinal disorders trials.

Carboplatin169 clinical trialsPembrolizumab145 clinical trialsCisplatin128 clinical trialsPemetrexed108 clinical trialsPaclitaxel80 clinical trialsDurvalumab71 clinical trialsAtezolizumab50 clinical trialsNivolumab49 clinical trialsSodium Chloride49 clinical trials
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