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Therapeutic area

Surgical and medical procedures

  • 434 clinical trials
  • 193 recruiting
  • 295 conditions
  • 27 countries

Conditions in this area

295 conditions with trials, the busiest first

Renal transplant56Allogenic stem cell transplantation19Analgesic therapy18Liver transplant14General anaesthesia12Hip arthroplasty11Postoperative analgesia10Cardiac operation9Haemodialysis9Influenza immunisation9Procedural pain9Prophylaxis against transplant rejection9Atrial fibrillation8Sedative therapy8Palliative care7Prophylaxis7Prophylaxis of nausea and vomiting7Thrombosis prophylaxis7Contraception6Heart transplant6Intensive care6Obesity6Pneumococcal immunisation6Human papilloma virus immunisation5+271

Clinical trials in Surgical and medical procedures

434 trials across Europe, recruiting first

Type of trial
Recruitment status
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434 clinical trials

Contraception+1

Recruiting

Contraceptive efficacy, safety and tolerability of drospirenone 4 mg (LPRI‑CF113) in healthy women of reproductive age over 13 cycles

InvestigationalNo placebo
Countries:CzechiaCzechia
  • Participants:0–17 years · 18–64 years · Healthy volunteers
  • Substances:DROSPIRENONE
  • Sponsor:Chemo Research S.L.

Smoking cessation therapy+1

Recruiting

Study on Cytisine for Quitting Nicotine E-Cigarettes and Tobacco in Motivated Individuals

Registered drug
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Cytisine
  • Sponsor:University of Rzeszow

Influenza+1

Recruiting

Efficacy and safety of the investigational mRNA influenza vaccine gskvx000000077430 (drug combination) in adults ≥ 65 years

Registered drugNo placebo
Countries:BelgiumBelgium
  • Participants:65+ years · Healthy volunteers
  • Substances:INFLUENZA A VIRUS, A/CROATIA/10136RV/2023 (H3N2) LIKE STRAIN X-425A, INACTIVATED
  • Sponsor:GlaxoSmithKline Biologicals

Renal transplant

Recruiting

Safety of Two Doses of Siplizumab Compared with Rabbit Anti‑Human Thymocyte Immunoglobulin in Kidney Transplant Recipients Receiving Standard Immunosuppression

Registered drug
Countries:AustriaAustria
  • Participants:18–64 years · 65+ years
  • Substances:Siplizumab

Pneumococcal immunisation

Recruiting

Safety of PF-07872412 versus 20‑valent pneumococcal conjugate vaccine in healthy infants for prevention of pneumococcal disease

Registered drugNo placebo
Countries:FinlandFinland
  • Participants:0–17 years
  • Substances:Pneumococcal Polysaccharide Serotype 1 Conjugated To Crm197 Adsorbed On Aluminium Phosphate
  • Sponsor:Pfizer Inc.

Fontan procedure

Recruiting

Spironolactone with drug combination to improve health in adults with Fontan circulation (clinical trial)

Registered drug
Countries:BelgiumBelgium
  • Participants:18–64 years
  • Substances:Dapagliflozin
  • Sponsor:UZ Leuven

Postoperative analgesia

Recruiting

Metamizole Sodium Monohydrate vs Sodium Chloride for Post‑Operative Pain Relief in Adults Undergoing Elective Laparoscopic Cholecystectomy

Registered drug
Countries:BelgiumBelgium
  • Participants:18–64 years · 65+ years
  • Substances:Sodium Chloride
  • Sponsor:UZ Leuven

Liver transplant

Recruiting

Everolimus-Based Calcineurin-Inhibitor-Free Immunosuppression with Drug Combination in Patients One Year After Liver Transplantation

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Ciclosporin
  • Sponsor:Medizinische Hochschule Hannover

Measles+3

Recruiting

Long‑term immunity after a 6‑month‑old MMR vaccine (live attenuated) in infants: follow‑up of antibody levels 1‑3 years after routine vaccination

Registered drugNo placebo
Countries:DenmarkDenmark
  • Participants:0–17 years · Healthy volunteers
  • Substances:RUBELLA VIRUS WISTAR RA 27/3 STRAIN (LIVE, ATTENUATED) PRODUCED IN HUMAN DIPLOID (MRC-5) CELLS
  • Sponsor:Region Hovedstaden

Labour induction

Recruiting

Study of Oral Misoprostol Combined with Osmotic Dilators for Labour Induction in Women with an Unprepared Cervix

Registered drugNo placebo
Countries:CzechiaCzechia
  • Participants:18–64 years
  • Substances:Misoprostol
  • Sponsor:Fakultni Nemocnice Brno

Pain+3

Recruiting

A study to evaluate the safety and how the body processes the combination of ibuprofen and paracetamol in children and adolescents with acute pain

Registered drugNo placebo
Countries:HungaryHungary
  • Participants:0–17 years
  • Substances:Ibuprofen
  • Sponsor:Aft Pharmaceuticals Limited

Peripheral arterial occlusive disease+5

Recruiting

A study comparing one month versus one year of aspirin and clopidogrel treatment in patients with chronic limb-threatening ischemia after below-the-knee vascular therapy.

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Clopidogrel
  • Sponsor:Fondation Hopital Saint Joseph

Substances studied in this area

The therapies tested most often in Surgical and medical procedures trials.

Sodium Chloride59 clinical trialsTacrolimus32 clinical trialsMycophenolate Mofetil18 clinical trialsPropofol15 clinical trialsParacetamol14 clinical trialsRopivacaine Hydrochloride13 clinical trialsApixaban11 clinical trialsDapagliflozin10 clinical trialsPotassium Chloride10 clinical trials
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