Algemeen Ziekenhuis Delta

The organisation investigates therapeutic interventions for disorders affecting the upper esophageal sphincter, with particular emphasis on conditions that impair normal physiological functions of the cricopharyngeus muscle. Research efforts concentrate on addressing functional abnormalities that prevent natural reflexive actions, specifically targeting retrograde cricopharyngeus dysfunction which manifests as an inability to perform certain protective and comfort-related physiological responses.

• Upper Esophageal Sphincter Dysfunction
• Cricopharyngeal Muscle Disorders
• Belching Disorders

The research explores innovative pharmacological approaches using neurotoxin-based interventions to modulate sphincter function and restore normal physiological reflexes in patients experiencing chronic symptoms related to esophageal motility impairment.