Clinical trials in Prague – page 21

1 217 clinical trials in Prague, Czechia across 18 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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1 217 trials in Prague

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Major depression

Recruiting

Study on the Effectiveness and Safety of NBI-1065845 for Adults with Major Depressive Disorder

Investigational

Study on the Effectiveness and Safety of NBI-1065845 for Adults with Major Depressive Disorder

Investigational

Czechia

Participants:18–64 years · 65+ years
Substances:9-(4-CYCLOHEXYLOXYPHENYL)-7-METHYL-3,4-DIHYDROPYRAZINO[2,1-C][1,2,4]THIADIAZINE 2,2-DIOXIDE
Sponsor:Neurocrine Biosciences Inc.

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Renal transplant+1

Recruiting

Study of Ravulizumab to Prevent Delayed Graft Function in Adult Patients After Kidney Transplant

Registered drug

Study of Ravulizumab to Prevent Delayed Graft Function in Adult Patients After Kidney Transplant

Registered drug

Czechia

Participants:18–64 years · 65+ years
Substances:Ravulizumab
Sponsor:Alexion Pharmaceuticals Inc.

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Non-small cell lung cancer

Recruiting

Study of Sigvotatug Vedotin and Pembrolizumab for Patients with Advanced Non-Small Cell Lung Cancer with High PD-L1 Levels

Registered drugNo placebo

Study of Sigvotatug Vedotin and Pembrolizumab for Patients with Advanced Non-Small Cell Lung Cancer with High PD-L1 Levels

Registered drugNo placebo

Czechia

Participants:18–64 years · 65+ years
Substances:Pembrolizumab
Sponsor:Pfizer Inc.

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Chronic lymphocytic leukaemia+1

Recruiting

Study Comparing BGB-16673 to Drug Combinations for Patients with Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Treated with BTK and BCL2 Inhibitors

Registered drugNo placebo

Study Comparing BGB-16673 to Drug Combinations for Patients with Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Treated with BTK and BCL2 Inhibitors

Registered drugNo placebo

Czechia

Participants:18–64 years · 65+ years
Substances:BGB-16673
Sponsor:BeOne Medicines AG

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Frontotemporal dementia

Recruiting

Study on the Safety and Effects of DNL593 for Patients with Frontotemporal Dementia

Registered drug

Study on the Safety and Effects of DNL593 for Patients with Frontotemporal Dementia

Registered drug

Czechia

Participants:18–64 years · 65+ years · Healthy volunteers
Substances:DNL593
Sponsor:Denali Therapeutics Inc.

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Varicella

Recruiting

Study on the Immune Response and Safety of a New Varicella Vaccine (GSKVX000000025896) Compared to Varicella Virus Oka/Merck Strain in Healthy Children Aged 12-15 Months

Registered drugNo placebo

Study on the Immune Response and Safety of a New Varicella Vaccine (GSKVX000000025896) Compared to Varicella Virus Oka/Merck Strain in Healthy Children Aged 12-15 Months

Registered drugNo placebo

Czechia

Participants:0–17 years · Healthy volunteers
Substances:GSKVX000000025896
Sponsor:GlaxoSmithKline Biologicals

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Hormone-refractory prostate cancer+1

Recruiting

Study Comparing Ifinatamab Deruxtecan and Docetaxel for Patients with Advanced Prostate Cancer Resistant to Hormone Therapy

Registered drugNo placebo

Study Comparing Ifinatamab Deruxtecan and Docetaxel for Patients with Advanced Prostate Cancer Resistant to Hormone Therapy

Registered drugNo placebo

Czechia

Participants:18–64 years · 65+ years
Substances:Codeine Phosphate
Sponsor:Merck Sharp & Dohme LLC

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Major depression

Recruiting

Study of milsaperidone as an additional treatment for adults with Major Depressive Disorder who are already taking antidepressants

Investigational

Study of milsaperidone as an additional treatment for adults with Major Depressive Disorder who are already taking antidepressants

Investigational

Czechia

Participants:18–64 years
Substances:(1S)-1-[4-[3-[4-(6-FLUORO-1,2-BENZOXAZOL-3-YL)PIPERIDIN-1-YL]PROPOXY]-3-METHOXYPHENYL]ETHANOL
Sponsor:Vanda Pharmaceuticals Netherlands B.V.

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Idiopathic pulmonary fibrosis+1

Recruiting

Long-Term Safety Study of Inhaled Pirfenidone for Patients with Progressive or Idiopathic Pulmonary Fibrosis

InvestigationalNo placebo

Long-Term Safety Study of Inhaled Pirfenidone for Patients with Progressive or Idiopathic Pulmonary Fibrosis

InvestigationalNo placebo

Czechia

Participants:18–64 years · 65+ years
Substances:Pirfenidone
Sponsor:Avalyn Pharma Inc.

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Hepatoblastoma+1

Recruiting

Study on the Safety and Effectiveness of Patritumab Deruxtecan for Children with Relapsed or Refractory Hepatoblastoma and Rhabdomyosarcoma

Registered drugNo placebo

Study on the Safety and Effectiveness of Patritumab Deruxtecan for Children with Relapsed or Refractory Hepatoblastoma and Rhabdomyosarcoma

Registered drugNo placebo

Czechia

Participants:0–17 years
Substances:Dexamethasone
Sponsor:Merck Sharp & Dohme LLC

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Chronic myelomonocytic leukaemia+1

Recruiting

Study Comparing Oral Azacitidine and Cedazuridine with Subcutaneous Azacitidine for Patients with Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia

Registered drugNo placebo

Study Comparing Oral Azacitidine and Cedazuridine with Subcutaneous Azacitidine for Patients with Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia

Registered drugNo placebo

Czechia

Participants:18–64 years · 65+ years
Substances:Azacitidine
Sponsor:Taiho Oncology Inc.

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Dementia Alzheimer's type

Recruiting

Study on ITI-1284 for Treating Agitation in Alzheimer's Patients

Investigational

Study on ITI-1284 for Treating Agitation in Alzheimer's Patients

Investigational

Czechia

Participants:18–64 years · 65+ years
Substances:Iti-1284
Sponsor:Intra-Cellular Therapies Inc.

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Clinical research in Prague

What the registry says about research in the country

01 Cardiology & Metabolic Disorders

Innovative research focusing on TTR amyloidosis and heart disease treatments, alongside studies investigating hypertriglyceridemia management with novel therapeutics.

Heart Disease Management
Metabolic Disorders
Cardiovascular Prevention

Multiple trials evaluating new therapeutic approaches for heart failure prevention and treatment.

02 Oncology Research

Comprehensive studies in prostate cancer and multiple myeloma, with particular focus on metastatic conditions and novel treatment combinations.

Metastatic Cancer Treatments
Gastric Cancer Therapies
Blood Cancer Research

Advanced trials comparing innovative therapies against standard treatments in various cancer types.

03 Immunology & Vaccines

Extensive vaccine development programs including meningococcal and chickenpox vaccines, alongside studies in immune system disorders.

Pediatric Vaccines
Immune System Disorders
Preventive Medicine

Focus on immunogenicity and safety in various age groups from infants to adults.

04 Respiratory & Inflammatory Conditions

Research into chronic rhinosinusitis and COPD, along with studies on inflammatory bowel conditions.

Respiratory Disease Management
Inflammatory Conditions
Autoimmune Disorders

Evaluating new therapeutic approaches for chronic respiratory and inflammatory conditions.

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