Therapeutic area

Musculoskeletal and connective tissue disorders – page 8

863 clinical trials
359 recruiting
328 conditions
28 countries

Clinical trials in Musculoskeletal and connective tissue disorders

863 trials across Europe, recruiting first

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863 clinical trials

Still's disease

Recruiting

Registered drugNo placebo

A Study of MAS825 in Children and Adults with Still's Disease to Test How Well It Works and How Safe It Is

Registered drugNo placebo

France

Participants:0–17 years · 18–64 years · 65+ years
Substances:Human Igg1 Monoclonal Antibody Against Human Il-1 Beta And Human Il-18
Sponsor:Novartis Pharma AG

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Osteoarthritis

Recruiting

Registered drug

Study of Methotrexate Treatment for Patients with Erosive Hand Osteoarthritis Not Responding to Standard Therapy

Registered drug

France

Participants:18–64 years · 65+ years
Substances:Folic Acid
Sponsor:Centre Hospitalier Universitaire De Nice

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Arthralgia

Recruiting

Registered drugNo placebo

Study of Platelet-Rich Plasma Injections Combined with Exercise Compared to Betamethasone and Ropivacaine for Chronic Shoulder Pain Treatment

Registered drugNo placebo

Spain

Participants:18–64 years · 65+ years
Substances:Platelet Concentrate
Sponsor:Asociacion Instituto De Investigacion Sanitaria Biobizkaia

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Spinal muscular atrophy

Recruiting

InvestigationalNo placebo

Study of Apitegromab Treatment in Children Under 2 Years Old with Spinal Muscular Atrophy (SMA)

InvestigationalNo placebo

Belgium

Participants:0–17 years
Substances:Apitegromab
Sponsor:Scholar Rock Inc.

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PIK3CA related overgrowth spectrum

Recruiting

InvestigationalNo placebo

Study of alpelisib in children and adults with PIK3CA-Related Overgrowth Spectrum (PROS)

InvestigationalNo placebo

Austria

Participants:0–17 years · 18–64 years · 65+ years
Substances:Alpelisib
Sponsor:Novartis Pharma AG

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Muscle spasticity

Recruiting

Registered drugNo placebo

Comparison of Pregabalin and Baclofen Treatment in Patients with Spastic Motor Behavior Following Cervical or Thoracic Spinal Cord Injury

Registered drugNo placebo

Czechia

Participants:18–64 years · 65+ years
Substances:Baclofen
Sponsor:Fakultni Nemocnice V Motole

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Hypochondroplasia

Recruiting

Registered drug

Study of Vosoritide Safety and Effectiveness in Infants and Young Children (0 to 36 months) with Hypochondroplasia

Registered drug

France

Participants:0–17 years
Substances:Vosoritide
Sponsor:Biomarin Pharmaceutical Inc.

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Myasthenia gravis

Recruiting

Investigational

Study of IMVT-1402 in Adults with Mild to Severe Generalized Myasthenia Gravis

Investigational

Czechia

Participants:18–64 years · 65+ years
Substances:IMEROPRUBART
Sponsor:Immunovant Sciences GmbH

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Back pain

Recruiting

Registered drug

Study comparing diclofenac, orphenadrine and paracetamol combination versus diclofenac alone and orphenadrine-paracetamol combination in patients with acute low back pain

Registered drug

Greece

Participants:18–64 years
Substances:DICLOFENAC POTASSIUM
Sponsor:Verisfield Single Member S.A.

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Desmoid tumour

Recruiting

InvestigationalNo placebo

Study of Nirogacestat in adult premenopausal women with desmoid tumors and aggressive fibromatosis to evaluate ovarian function recovery

InvestigationalNo placebo

Belgium

Participants:18–64 years
Substances:Nirogacestat Hydrobromide
Sponsor:Springworks Therapeutics Inc.

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Systemic scleroderma+3

Recruiting

Registered drugNo placebo

Study of AlloNK and rituximab with cyclophosphamide and fludarabine in adults with relapsing rheumatoid arthritis, inflammatory myopathies, systemic sclerosis, or Sjögren's disease

Registered drugNo placebo

Bulgaria

Participants:18–64 years · 65+ years
Substances:Cyclophosphamide
Sponsor:Artiva Biotherapeutics Inc.

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Osteoporosis postmenopausal

Recruiting

Registered drug

Study of Everolimus and Resistance Training to Improve Bone Formation in Healthy Postmenopausal Women

Registered drug

Denmark

Participants:65+ years · Healthy volunteers
Substances:Everolimus
Sponsor:Odense University Hospital

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Substances studied in this area

The therapies tested most often in Musculoskeletal and connective tissue disorders trials.

Sodium Chloride47 clinical trials Paracetamol32 clinical trials Tocilizumab29 clinical trials Methotrexate25 clinical trials Adalimumab23 clinical trials Rituximab23 clinical trials Cyclophosphamide20 clinical trials Etanercept19 clinical trials Baricitinib17 clinical trials

Musculoskeletal and connective tissue disorders – page 8

Conditions in this area

Clinical trials in Musculoskeletal and connective tissue disorders

863 clinical trials

Still's disease

A Study of MAS825 in Children and Adults with Still's Disease to Test How Well It Works and How Safe It Is

Osteoarthritis

Study of Methotrexate Treatment for Patients with Erosive Hand Osteoarthritis Not Responding to Standard Therapy

Arthralgia

Study of Platelet-Rich Plasma Injections Combined with Exercise Compared to Betamethasone and Ropivacaine for Chronic Shoulder Pain Treatment

Spinal muscular atrophy

Study of Apitegromab Treatment in Children Under 2 Years Old with Spinal Muscular Atrophy (SMA)

PIK3CA related overgrowth spectrum

Study of alpelisib in children and adults with PIK3CA-Related Overgrowth Spectrum (PROS)

Muscle spasticity

Comparison of Pregabalin and Baclofen Treatment in Patients with Spastic Motor Behavior Following Cervical or Thoracic Spinal Cord Injury

Hypochondroplasia

Study of Vosoritide Safety and Effectiveness in Infants and Young Children (0 to 36 months) with Hypochondroplasia

Myasthenia gravis

Study of IMVT-1402 in Adults with Mild to Severe Generalized Myasthenia Gravis

Back pain

Study comparing diclofenac, orphenadrine and paracetamol combination versus diclofenac alone and orphenadrine-paracetamol combination in patients with acute low back pain

Desmoid tumour

Study of Nirogacestat in adult premenopausal women with desmoid tumors and aggressive fibromatosis to evaluate ovarian function recovery

Systemic scleroderma+3

Study of AlloNK and rituximab with cyclophosphamide and fludarabine in adults with relapsing rheumatoid arthritis, inflammatory myopathies, systemic sclerosis, or Sjögren's disease

Osteoporosis postmenopausal

Study of Everolimus and Resistance Training to Improve Bone Formation in Healthy Postmenopausal Women

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Substances studied in this area

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