Azienda Sociosanitaria Territoriale Santi Paolo E Carlo

At Azienda Sociosanitaria Territoriale Santi Paolo E Carlo in Milan, a major share of the clinical research focuses on HIV infections, HIV-1 infection, and mpox virus disease. These studies are designed to assess new antiviral options, improve treatment switching strategies, and better understand outcomes in people living with or newly diagnosed with viral infections.

• Evaluation of new antiviral therapies for HIV-1
• Studies on treatment switching and long-term control in HIV
• Clinical observations in mpox virus disease to guide care

The site’s infectious diseases team is building evidence to support safer, more effective management of viral illnesses in everyday practice.

Research in respiratory diseases includes chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, and progressive pulmonary fibrosis. These trials aim to reduce flare-ups, slow lung function decline, and evaluate whether emerging treatments can improve breathing and quality of life for people with chronic lung disease.

• Testing therapies for COPD with frequent exacerbations
• Assessing treatments for idiopathic pulmonary fibrosis and progressive pulmonary fibrosis
• Exploring ways to lower disease burden in long-term lung disease

This area reflects a strong interest in improving outcomes for patients with complex and progressive respiratory conditions.

The site is also active in ophthalmic research, with studies in glaucoma, neurotrophic keratopathy, and seasonal allergic conjunctivitis. These trials are focused on preserving vision, easing eye symptoms, and evaluating new approaches that may help protect eye health in people with chronic or inflammatory eye disorders.

• Improving visual field preservation in glaucoma
• Testing treatments for corneal nerve damage in neurotrophic keratopathy
• Relieving symptoms of seasonal allergic conjunctivitis

The ophthalmology studies combine symptom control with efforts to maintain long-term vision and eye function.

In the cardiovascular field, clinical trials at this site examine heart failure and pulmonary hypertension due to left heart disease, stroke, and the reversal of anticoagulation in urgent surgical settings. The research is aimed at improving survival, reducing complications, and supporting safer treatment decisions in time-sensitive cardiovascular care.

• Evaluating therapies for heart failure with pulmonary hypertension
• Studying treatment effectiveness after stroke
• Improving bleeding control and urgent care for patients on anticoagulants

These studies address both chronic cardiovascular disease and emergency management needs.

The site’s work in digestive system diseases includes research on cholestasis, while related studies also address chronic kidney disease associated with type 1 diabetes. Together, these trials are examining new ways to reduce symptoms, protect organ function, and improve disease control in patients with long-term metabolic and hepatobiliary conditions.

• Testing treatments for cholestatic pruritus
• Evaluating kidney-protective strategies in chronic kidney disease with type 1 diabetes
• Supporting better management of complex multi-organ disease

At this Milan hospital, the research portfolio shows a broad interest in chronic conditions that affect quality of life and long-term health.