IRCCS Policlinico San Donato

At IRCCS Policlinico San Donato, research in congenital and hereditary disorders focuses on hereditary angioedema, with studies aimed at improving preventive care and understanding treatment performance in younger patients.

• Evaluating new options for the prophylactic management of hereditary angioedema
• Studying safety and how the body handles treatment in pediatric patients with C1-inhibitor hereditary angioedema
• Supporting better long-term control of a rare inherited condition

This area brings together rare-disease expertise with a strong focus on testing therapies that may help reduce attacks and improve day-to-day stability for affected children and families.

Clinical trials in digestive system diseases at this site center on ulcerative colitis, a chronic inflammatory bowel disease, with the goal of improving symptom control and intestinal healing.

• Assessing whether new therapies can improve endoscopic outcomes and symptomatic remission
• Comparing treatment effectiveness in moderately to severely active ulcerative colitis
• Advancing care for patients living with persistent intestinal inflammation

The research reflects a practical effort to find better ways to control disease activity, ease ongoing symptoms, and support more durable remission for people with this condition.

The nutritional and metabolic disease portfolio includes studies in obesity and overweight, exploring whether new treatments can improve health outcomes and reduce related medical risks.

• Testing therapies intended to support weight management and broader health improvement
• Evaluating whether treatment can lower morbidity and mortality in adults with obesity
• Addressing the long-term burden of excess body weight and related complications

This work highlights an important area of metabolic research, with a focus on helping patients achieve meaningful health benefits beyond weight reduction alone.