A Phase 3 Study of Orelabrutinib to Delay Disability Progression in Patients with Non‑Active Secondary Progressive Multiple Sclerosis
- Substances:–
Croatia- Participants:18–64 years
- Sponsor:Zenas Biopharma (USA) LLC
Rare diseases
Investigational molecules
Locations
Ulica Mije Kispatica 12, 10000 Zagreb, Croatia
KBC Zagreb in Zagreb, Croatia specialises in clinical trials of conditions such as Colitis ulcerative, Crohn's disease, Dementia Alzheimer's type, Factor VIII deficiency, and other specialisations. This site conducts important research.
The medical center is at the forefront of research in Crohn's Disease, focusing on innovative treatments to achieve remission. The ongoing studies aim to enhance the understanding of disease mechanisms and improve patient outcomes.
Through these studies, the center contributes significantly to the development of new therapeutic strategies for managing Crohn's Disease.
Specializing in Multiple Sclerosis, the center conducts extensive research to evaluate the effectiveness of various therapies. These efforts are crucial in advancing treatment options for both relapsing and progressive forms of the disease.
The center's research is pivotal in improving the quality of life for patients with Multiple Sclerosis through innovative therapeutic approaches.
Research at the center includes cutting-edge studies on Diffuse Large B-Cell Lymphoma (DLBCL), focusing on novel cell therapies and combination treatments to enhance patient response rates.
These studies are instrumental in developing more effective treatment protocols for DLBCL, particularly in relapsed or refractory cases.
The center is actively involved in research on Ulcerative Colitis, exploring the efficacy and safety of new maintenance therapies to manage this chronic condition.
By advancing knowledge in this area, the center aims to provide better therapeutic options for patients with Ulcerative Colitis.
Focusing on Myeloproliferative Neoplasms, the center's research includes evaluating the safety and efficacy of novel drug combinations, contributing to improved management of these complex disorders.
The center's work is crucial in developing new treatment paradigms for patients with Myeloproliferative Neoplasms.
In the field of Breast Cancer, the center is pioneering research on patient-centered treatment approaches, including home administration of therapies to enhance patient convenience and adherence.
This research is vital in improving the overall treatment experience for patients with HER2-positive breast cancer.
The center is dedicated to advancing treatment for Schizophrenia, focusing on adjunctive therapies to improve symptom management in patients with inadequate response to standard treatments.
These efforts are essential in enhancing therapeutic outcomes for individuals living with Schizophrenia.
Research on Solid Tumors at the center includes evaluating the safety and pharmacokinetics of novel drug combinations, aiming to improve treatment efficacy for advanced cancer patients.
The center's work is pivotal in developing new therapeutic options for patients with challenging solid tumors.
Specializing in Non-Small Cell Lung Cancer with ROS1 gene rearrangements, the center conducts comparative studies to identify superior treatment options for patients with CNS metastases.
This research is crucial in optimizing treatment strategies for this specific subset of lung cancer patients.
The center is engaged in research on Alzheimer's Disease, focusing on the long-term safety and tolerability of treatments for psychosis associated with the condition.
These studies are vital in improving the management of neuropsychiatric symptoms in Alzheimer's patients.
Research at the center includes evaluating new treatments for Bullous Pemphigoid, aiming to achieve sustained remission and improve patient quality of life.
The center's work is instrumental in advancing therapeutic options for this autoimmune blistering disorder.
In the field of Haemophilia, the center is exploring prophylactic treatments to reduce bleeding episodes in patients with inhibitors, contributing to better disease management.
This research is essential in enhancing the quality of life for patients with Haemophilia A and B with inhibitors.
The center is advancing research in Bipolar Disorder, focusing on the efficacy of new treatments for managing manic episodes, thereby improving patient outcomes.
These studies are crucial in developing effective therapeutic strategies for individuals with Bipolar I Disorder.
Research on Hidradenitis Suppurativa at the center involves evaluating new treatments to alleviate symptoms and improve patient quality of life.
The center's work is pivotal in providing new therapeutic options for this chronic inflammatory skin condition.
The center is engaged in research on Spinal Muscular Atrophy, focusing on combination therapies to enhance treatment efficacy and patient outcomes.
This research is vital in advancing therapeutic options for individuals with Spinal Muscular Atrophy.
In the area of Acute Major Bleeding, the center is investigating the effectiveness of new treatments to reverse anticoagulant effects, aiming to improve patient safety and outcomes.
The center's research is crucial in developing protocols for managing bleeding complications in patients on anticoagulant therapy.
Clinical trials currently enrolling participants at this site.
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