Universitaetsklinikum Aachen AöR

Clinical research here spans critical care, cardiovascular diseases, kidney disorders, and analytical and therapeutic techniques. The trials often focus on improving treatment effectiveness, refining diagnosis, and supporting recovery in seriously ill patients.

• Research in intensive care and critical illness, including sepsis, acute kidney injury, and postoperative complications
• Cardiovascular research on heart failure, atrial fibrillation, atherosclerotic disease, and surgical risk reduction
• Kidney-focused studies covering chronic kidney disease, IgA nephropathy, FSGS, and transplant-related care

The site also contributes to studies that test better ways to protect organs during major surgery and to improve outcomes for patients in complex hospital-based care.

A major part of the trial portfolio addresses blood cancers, myeloproliferative neoplasms, and transplant medicine. Research is aimed at improving survival, reducing relapse, and making transplant-related treatment safer and more effective.

• Leukemia studies in AML, ALL, and CML, including treatment strategies for newly diagnosed and relapsed disease
• Lymphoma research for diffuse large B-cell lymphoma, Hodgkin lymphoma, and other aggressive subtypes
• Transplant and graft-versus-host disease studies focused on prevention, conditioning, and long-term care

At Universitaetsklinikum Aachen AöR, this field combines standard oncology care with trials exploring more personalized and less toxic treatment approaches.

The site conducts extensive research in solid tumors, especially breast cancer, lung cancer, prostate cancer, gastrointestinal cancers, and gynecologic cancers. Many studies aim to improve survival before and after surgery or to test new combinations that strengthen cancer control.

• Breast cancer trials for early, locally advanced, and metastatic disease
• Prostate and bladder cancer studies, including work on recurrence, metastatic disease, and imaging-guided care
• Gastrointestinal and hepatobiliary cancer research involving gastric, pancreatic, colorectal, cholangiocarcinoma, and liver cancers

These trials reflect a strong interest in multimodal cancer treatment, with the goal of improving outcomes while supporting surgical decision-making.

Research in this area covers neurological diseases and mental health conditions, with studies in epilepsy, Alzheimer’s disease, stroke, multiple sclerosis, and schizophrenia. The main purpose is to improve symptom control, slow disease progression, and support brain health over time.

• Epilepsy studies focused on reducing seizure frequency and improving long-term control
• Alzheimer’s disease research aimed at earlier detection and slowing cognitive decline
• Psychiatric and neuroinflammatory disorders including treatment-resistant schizophrenia, multiple sclerosis, and movement-related conditions

This research area shows a broad commitment to both neurological care and cognitive health across different stages of disease.

The trial portfolio also includes immune system diseases, inflammatory disorders, and several rare diseases. Studies are designed to better control inflammation, reduce organ damage, and improve quality of life in chronic conditions.

• Autoimmune kidney diseases such as lupus nephritis and IgA nephropathy
• Inflammatory skin and bowel diseases including ulcerative colitis, hidradenitis suppurativa, and prurigo nodularis
• Rare hematologic and mast cell disorders such as systemic mastocytosis, paroxysmal nocturnal hemoglobinuria, and myelofibrosis

These studies at Universitaetsklinikum Aachen AöR highlight an active interest in conditions where better targeted treatment options are still needed.