Clinical trials in Leuven – page 40

1 129 clinical trials in Leuven, Belgium across 3 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

Leuven at a glance

1 129

clinical trials

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1 129 trials in Leuven

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Dilated cardiomyopathy

Not yet recruiting

Long‑Term Safety and Efficacy Study of Danicamtiv in Adults with Symptomatic Genetic and Familial Dilated Cardiomyopathy

InvestigationalNo placebo

Long‑Term Safety and Efficacy Study of Danicamtiv in Adults with Symptomatic Genetic and Familial Dilated Cardiomyopathy

InvestigationalNo placebo

Belgium

Participants:18–64 years · 65+ years
Substances:Danicamtiv
Sponsor:Kardigan Inc.

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Systemic lupus erythematosus

Not yet recruiting

Study of dapirolizumab pegol placental transfer to infants in pregnant women with active systemic lupus erythematosus (drug combination)

Registered drugNo placebo

Study of dapirolizumab pegol placental transfer to infants in pregnant women with active systemic lupus erythematosus (drug combination)

Registered drugNo placebo

Belgium

Participants:0–17 years · 18–64 years
Substances:Benzocaine
Sponsor:UCB Biopharma

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Endometrial cancer

Not yet recruiting

Study of Dostarlimab in Young Women with Newly Diagnosed MMR‑deficient Endometrial Cancer Who Want to Preserve Fertility

Registered drugNo placebo

Study of Dostarlimab in Young Women with Newly Diagnosed MMR‑deficient Endometrial Cancer Who Want to Preserve Fertility

Registered drugNo placebo

Belgium

Participants:18–64 years
Substances:Dostarlimab
Sponsor:UZ Leuven

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Type 2 diabetes mellitus

Not yet recruiting

Phase 3 Study of Oral Orforglipron vs Weekly Dulaglutide in Children and Adolescents (10‑<18 years) with Type 2 Diabetes

Registered drugNo placebo

Phase 3 Study of Oral Orforglipron vs Weekly Dulaglutide in Children and Adolescents (10‑<18 years) with Type 2 Diabetes

Registered drugNo placebo

Belgium

Participants:0–17 years
Substances:Dulaglutide
Sponsor:Eli Lilly & Co.

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Crohn's disease

Not yet recruiting

Efficacy and safety of ontunisertib in patients with fibrostenosing Crohn’s disease: a phase 2b randomized, double‑blind, placebo‑controlled dose‑ranging trial

Investigational

Efficacy and safety of ontunisertib in patients with fibrostenosing Crohn’s disease: a phase 2b randomized, double‑blind, placebo‑controlled dose‑ranging trial

Investigational

Belgium

Participants:18–64 years · 65+ years
Substances:ORG-129
Sponsor:Agomab Spain S.L.U.

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Systemic lupus erythematosus

Not yet recruiting

Study of subcutaneous anifrolumab pharmacokinetics, pharmacodynamics and safety in children aged 5 to <18 years with systemic lupus erythematosus

Registered drugNo placebo

Study of subcutaneous anifrolumab pharmacokinetics, pharmacodynamics and safety in children aged 5 to <18 years with systemic lupus erythematosus

Registered drugNo placebo

Belgium

Participants:0–17 years
Substances:Anifrolumab
Sponsor:AstraZeneca AB

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Idiopathic pulmonary fibrosis

Not yet recruiting

Randomized Phase 3 Study of Deupirfenidone (LYT‑100) versus Pirfenidone in Adults with Idiopathic Pulmonary Fibrosis

Registered drugNo placebo

Randomized Phase 3 Study of Deupirfenidone (LYT‑100) versus Pirfenidone in Adults with Idiopathic Pulmonary Fibrosis

Registered drugNo placebo

Belgium

Participants:18–64 years · 65+ years
Substances:Deupirfenidone
Sponsor:Puretech Lyt 100 Inc.

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Autoimmune hepatitis

Not yet recruiting

A Phase 2/3 Randomized Double‑Blind Study of Inebilizumab for Safety and Tolerability in Patients with Autoimmune Hepatitis

Registered drug

A Phase 2/3 Randomized Double‑Blind Study of Inebilizumab for Safety and Tolerability in Patients with Autoimmune Hepatitis

Registered drug

Belgium

Participants:18–64 years · 65+ years
Substances:Inebilizumab
Sponsor:Amgen Inc.

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Attention deficit hyperactivity disorder

Not yet recruiting

Effect of Methylphenidate versus Placebo on Attachment‑Related Learning in Children with Attention‑Deficit/Hyperactivity Disorder (ADHD)

Registered drug

Effect of Methylphenidate versus Placebo on Attachment‑Related Learning in Children with Attention‑Deficit/Hyperactivity Disorder (ADHD)

Registered drug

Belgium

Participants:0–17 years
Substances:Methylphenidate Hydrochloride
Sponsor:UZ Leuven

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Sjogren's syndrome

Not yet recruiting

Efficacy and safety of efgartigimod alfa in adults with Sjögren’s disease‑associated sensorimotor or sensory polyneuropathy: a phase 2 randomized placebo‑controlled study

Registered drug

Efficacy and safety of efgartigimod alfa in adults with Sjögren’s disease‑associated sensorimotor or sensory polyneuropathy: a phase 2 randomized placebo‑controlled study

Registered drug

Belgium

Participants:18–64 years · 65+ years
Substances:Efgartigimod Alfa
Sponsor:Argenx

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Chronic graft versus host disease

Not yet recruiting

Study of belumosudil versus drug combination in patients aged 12 years and older with chronic graft‑versus‑host disease refractory after prior therapy

Registered drugNo placebo

Study of belumosudil versus drug combination in patients aged 12 years and older with chronic graft‑versus‑host disease refractory after prior therapy

Registered drugNo placebo

Belgium

Participants:0–17 years · 18–64 years · 65+ years
Substances:Bortezomib
Sponsor:Sanofi-Aventis Recherche & Developpement

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Hormone receptor positive breast cancer

Not yet recruiting

Evaluating tirzepatide and letrozole for reducing tumor growth in postmenopausal hormone‑receptor‑positive breast cancer patients

Registered drugNo placebo

Evaluating tirzepatide and letrozole for reducing tumor growth in postmenopausal hormone‑receptor‑positive breast cancer patients

Registered drugNo placebo

Belgium

Participants:18–64 years · 65+ years
Substances:Letrozole
Sponsor:UZ Leuven

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Clinical research in Leuven

What the registry says about research in the country

01 Gastrointestinal Research

Clinical investigations focusing on ulcerative colitis and innovative treatments for inflammatory bowel conditions. Studies include evaluation of novel therapies for short bowel syndrome and gastrointestinal motility disorders.

Inflammatory Bowel Disease Treatment
Gastrointestinal Motility Studies
Metabolic Disease Research

Current trials are examining drug absorption and therapeutic responses in patients with various digestive conditions.

02 Oncology Studies

Groundbreaking research in head and neck cancer treatments, including innovative radiotherapy approaches. Studies are also investigating new therapies for bladder cancer, focusing on early-stage interventions.

Advanced Cancer Therapies
Immunotherapy Research
Non-invasive Treatment Approaches

Emphasis on combining traditional treatments with novel therapeutic approaches to improve patient outcomes.

03 Neurological Disorders

Comprehensive studies on Alzheimer's disease and frontotemporal dementia, investigating disease progression and potential treatments. Research includes innovative approaches to understanding brain circuit functionality.

Cognitive Function Studies
Neurodegenerative Disease Research
Brain Imaging Technologies

Advanced imaging techniques are being utilized to track disease progression and treatment effectiveness.

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Clinical trials in Leuven – page 40

1 129 trials in Leuven

Dilated cardiomyopathy

Long‑Term Safety and Efficacy Study of Danicamtiv in Adults with Symptomatic Genetic and Familial Dilated Cardiomyopathy

Systemic lupus erythematosus

Study of dapirolizumab pegol placental transfer to infants in pregnant women with active systemic lupus erythematosus (drug combination)

Endometrial cancer

Study of Dostarlimab in Young Women with Newly Diagnosed MMR‑deficient Endometrial Cancer Who Want to Preserve Fertility

Type 2 diabetes mellitus

Phase 3 Study of Oral Orforglipron vs Weekly Dulaglutide in Children and Adolescents (10‑<18 years) with Type 2 Diabetes

Crohn's disease

Efficacy and safety of ontunisertib in patients with fibrostenosing Crohn’s disease: a phase 2b randomized, double‑blind, placebo‑controlled dose‑ranging trial

Systemic lupus erythematosus

Study of subcutaneous anifrolumab pharmacokinetics, pharmacodynamics and safety in children aged 5 to <18 years with systemic lupus erythematosus

Idiopathic pulmonary fibrosis

Randomized Phase 3 Study of Deupirfenidone (LYT‑100) versus Pirfenidone in Adults with Idiopathic Pulmonary Fibrosis

Autoimmune hepatitis

A Phase 2/3 Randomized Double‑Blind Study of Inebilizumab for Safety and Tolerability in Patients with Autoimmune Hepatitis

Attention deficit hyperactivity disorder

Effect of Methylphenidate versus Placebo on Attachment‑Related Learning in Children with Attention‑Deficit/Hyperactivity Disorder (ADHD)

Sjogren's syndrome

Efficacy and safety of efgartigimod alfa in adults with Sjögren’s disease‑associated sensorimotor or sensory polyneuropathy: a phase 2 randomized placebo‑controlled study

Chronic graft versus host disease

Study of belumosudil versus drug combination in patients aged 12 years and older with chronic graft‑versus‑host disease refractory after prior therapy

Hormone receptor positive breast cancer

Evaluating tirzepatide and letrozole for reducing tumor growth in postmenopausal hormone‑receptor‑positive breast cancer patients

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