Therapeutic area

Blood and lymphatic system disorders – page 95

1 200 clinical trials
457 recruiting
364 conditions
27 countries

Clinical trials in Blood and lymphatic system disorders

1 200 trials across Europe, recruiting first

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1 200 clinical trials

Factor IX deficiency

Not recruiting

InvestigationalNo placebo

Study on the Efficacy and Safety of Fidanacogene Elaparvovec Gene Therapy in Adult Males with Moderate to Severe Hemophilia B

InvestigationalNo placebo

Belgium

Participants:18–64 years
Substances:Fidanacogene Elaparvovec
Sponsor:Pfizer Inc.

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Haemophilia

Not recruiting

Registered drugNo placebo

Study on Fitusiran for Preventing Bleeding in Males Aged 12 and Older with Severe Hemophilia A or B, with or without Inhibitors

Registered drugNo placebo

France

Participants:0–17 years · 18–64 years · 65+ years
Substances:Fitusiran
Sponsor:Sanofi-Aventis Recherche & Developpement

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Thalassaemia alpha

Not recruiting

Registered drug

Study on Luspatercept for Treating Anemia in Adults and Adolescents with Alpha-Thalassemia

Registered drug

Greece

Participants:0–17 years · 18–64 years · 65+ years
Substances:Luspatercept
Sponsor:Celgene Corp.

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Familial haemophagocytic lymphohistiocytosis+1

Not recruiting

InvestigationalNo placebo

Study on Tadekinig Alfa for Patients with NLRC4 Mutation and XIAP Deficiency

InvestigationalNo placebo

Germany

Participants:0–17 years
Substances:Tadekinig Alfa
Sponsor:AB2 Bio S.A.

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Leukocyte adhesion deficiency+1

Not recruiting

InvestigationalNo placebo

Study on Long-Term Safety and Efficacy of Gene Therapy for Leukocyte Adhesion Deficiency-I Using RP-L201 in Patients with LAD-I

InvestigationalNo placebo

Spain

Participants:0–17 years · 18–64 years
Substances:Autologous Cd34+ Haematopoietic Stem Cells Genetically Modified With Lentiviral Vector Encoding The Cd18 Gene
Sponsor:Rocket Pharmaceuticals Inc.

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Diffuse large B-cell lymphoma refractory+1

Not recruiting

Registered drugNo placebo

Study on the Safety and Effectiveness of ALLO-501A and ALLO-647 for Adults with Relapsed or Refractory Large B-Cell Lymphoma

Registered drugNo placebo

Italy

Participants:18–64 years · 65+ years
Substances:Allo-501A
Sponsor:Allogene Therapeutics Inc.

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Sickle cell anaemia with crisis+1

Not recruiting

Investigational

Study on Crovalimab for Preventing Painful Episodes in Sickle Cell Disease Patients

Investigational

France

Participants:0–17 years · 18–64 years
Sponsor:F. Hoffmann-La Roche AG

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Acute myeloid leukaemia

Not recruiting

Registered drugNo placebo

Study of Magrolimab and Chemotherapy for Newly Diagnosed Acute Myeloid Leukemia Patients Eligible for Stem Cell Transplantation

Registered drugNo placebo

Germany

Participants:18–64 years · 65+ years
Substances:Cytarabine
Sponsor:Universitaet Leipzig

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Warm autoimmune haemolytic anaemia

Not recruiting

Investigational

Study of Obexelimab for Patients with Warm Autoimmune Hemolytic Anemia

Investigational

Italy

Participants:18–64 years · 65+ years
Substances:Obexelimab
Sponsor:Zenas Biopharma (USA) LLC

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Sickle cell anaemia with crisis+1

Not recruiting

Investigational

Study on the Safety and Effects of Crovalimab for Treating Vaso-Occlusive Episodes in Sickle Cell Disease Patients

Investigational

France

Participants:0–17 years · 18–64 years
Substances:Crovalimab
Sponsor:F. Hoffmann-La Roche AG

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Polycythaemia vera

Not recruiting

Investigational

Study of SLN124 for Patients with Polycythemia Vera

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Substances:Synthetic Double-Stranded Sirna Oligonucleotide Directed Against Tmprss6 Mrna And Covalently Linked To A Ligand Containing Three N-Acetylgalactosamine Residues
Sponsor:Silence Therapeutics PLC

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Factor VIII deficiency+3

Not recruiting

InvestigationalNo placebo

Study on the Safety and Effectiveness of SerpinPC for Patients with Severe Hemophilia A or B

InvestigationalNo placebo

Belgium

Participants:0–17 years · 18–64 years
Sponsor:Apcintex Limited

Contact Research Centre

Substances studied in this area

The therapies tested most often in Blood and lymphatic system disorders trials.

Dexamethasone139 clinical trials Rituximab122 clinical trials Venetoclax114 clinical trials Cyclophosphamide99 clinical trials Lenalidomide98 clinical trials Cytarabine77 clinical trials Daratumumab74 clinical trials Azacitidine65 clinical trials Bortezomib64 clinical trials

Blood and lymphatic system disorders – page 95

Conditions in this area

Clinical trials in Blood and lymphatic system disorders

1 200 clinical trials

Factor IX deficiency

Study on the Efficacy and Safety of Fidanacogene Elaparvovec Gene Therapy in Adult Males with Moderate to Severe Hemophilia B

Haemophilia

Study on Fitusiran for Preventing Bleeding in Males Aged 12 and Older with Severe Hemophilia A or B, with or without Inhibitors

Thalassaemia alpha

Study on Luspatercept for Treating Anemia in Adults and Adolescents with Alpha-Thalassemia

Familial haemophagocytic lymphohistiocytosis+1

Study on Tadekinig Alfa for Patients with NLRC4 Mutation and XIAP Deficiency

Leukocyte adhesion deficiency+1

Study on Long-Term Safety and Efficacy of Gene Therapy for Leukocyte Adhesion Deficiency-I Using RP-L201 in Patients with LAD-I

Diffuse large B-cell lymphoma refractory+1

Study on the Safety and Effectiveness of ALLO-501A and ALLO-647 for Adults with Relapsed or Refractory Large B-Cell Lymphoma

Sickle cell anaemia with crisis+1

Study on Crovalimab for Preventing Painful Episodes in Sickle Cell Disease Patients

Acute myeloid leukaemia

Study of Magrolimab and Chemotherapy for Newly Diagnosed Acute Myeloid Leukemia Patients Eligible for Stem Cell Transplantation

Warm autoimmune haemolytic anaemia

Study of Obexelimab for Patients with Warm Autoimmune Hemolytic Anemia

Sickle cell anaemia with crisis+1

Study on the Safety and Effects of Crovalimab for Treating Vaso-Occlusive Episodes in Sickle Cell Disease Patients

Polycythaemia vera

Study of SLN124 for Patients with Polycythemia Vera

Factor VIII deficiency+3

Study on the Safety and Effectiveness of SerpinPC for Patients with Severe Hemophilia A or B

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Substances studied in this area

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